I faced following error.
MS .NET framework error popup screen appear "Interrupted .NET framework unhandled exception has occurred in a component. When click the details. It has 100 components are interrupted. But it saved last modification. Confirmed

Question

Encountered same issue for each tag modification for any required reason such as description and setpoint values assigning. 
 This shut down event is not being logged when checked and observed during face the mentioned issue. 
 Same shut down (Crash window maker app). Faced while editing Data Change scripting. But did not face in Application/Condition type of script modification even without modification just pressing window cross / cancel button on the script editor window. 
 other HMI application were tested there is no such error. so We can say InTouch HMI working with well configured HMI application. 
 May I know your comment if you had that kind of issue. 
 in advance thanks your support

Richard Köhlerstrand · Answer

Hi Ahmet, 
 You should reach out to techsupport to get this sorted out, but it initially looks like some corruption in your application, you should first try to rebuild your application to see if that resolves your issue. 
 The steps are described in the following technote, but in general it means that you create a new application, import the tag database, windows, scripts, and if used, also Industrial Graphics. there is also methods of transferring any specific Window Viewer configuration if needed. 
 These steps should not be that time consuming and will tell you if there is a issue in your application. 
 https://softwaresupportsp.aveva.com/#/knowledgebase/details/000022731?lang=en_us 
 Let me know how this works out for you.

I faced following error. MS .NET framework error popup screen appear "Interrupted .NET framework unhandled exception has occurred in a component. When click the details. It has 100 components are interrupted. But it saved last modification. Confirmed