Menu configuration

Is there any way to change Level 2 and Level 3 Pages displayed on the SA navigation pane based on a selection. What we have is multiple clusters which are being monitored by a single project. So the home page will have a selection which determines the site you want to look at, which will in turn modify the navigation pane. I need to know if this is possible in the situation awareness project?

In simple terms what I am asking is, is it possible to change the situation awareness navigation pane dynamically on a runtime project?